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For laboratory research purposes only. Not for human or animal consumption.
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All products sold on this website are intended for laboratory research purposes only. They are not intended for human or animal consumption, medical use, or therapeutic use.
MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a mitochondria-derived peptide (MDP) encoded within the 12S ribosomal RNA gene of the mitochondrial genome, representing a novel class of signalling peptides of significant interest to researchers studying mitochondrial biology and metabolic regulation. Comprising 16 amino acids, MOTS-c has been studied for its role in regulating the AMPK pathway, folate-methionine cycle, and nuclear gene expression in response to metabolic stress, positioning it as a compound of interest in research into cellular energy homeostasis, insulin sensitivity, and mitochondria-to-nucleus retrograde signalling. Supplied as a lyophilised powder with ≥98% purity (HPLC verified), this product is intended exclusively for in vitro and laboratory research use.